Clinical Pharmacology Details


CLEMASTINE


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Indications & Dose:

Symptomatic relief of allergy such as hay fever, urticaria



Adult: 1 mg twice daily, increased if necessary up to 6 mg daily


OR


Adult: 1 mg twice daily oral or injectable DS Tabs one tab once daily


Children


Tab: under 3 years not recommended 3-6 years,1/2 tablet Over 6 years,1/2-1 tablet all twice daily taken night and morning.


Syp


Adult : 10 ml at night and morning


Children: Under 1 years not recommended


1-3- years; 2.5ml-5ml 3-6 year,5ml


Over 6 year 5-10ml all twice daily taken night and morning 

Contraindications:

Narrow angle glaucoma, bladder neck obstruction 

Side Effects:

Cautions:

Precautions:

Liver disease, elderly, increased intraocular pressure, hyperthyroidism, cardiovascular disease, hypertension, urinary retention, renal disease, stenosed peptic ulcer

Interaction:

Warnings:

Adverse Effects:

Lactations:

wsiness and irritability in nursing infant; use with caution during breast feeding 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Anxiety, confusion, dizziness, drowsiness, euphoria, fatigue, neuritis, paresthesia, poor coordination


CV: Hypotension, palpitations, tachycardia


EENT: Blurred vision, dry nose, throat; mydriasis, nasal stuffiness, tinnitus


GI: Anorexia, constipation, diarrhea, dry mouth, nausea, vomiting


GU: Dysuria, frequency, impotence, retention


HEME: Agranulocytosis, hemolytic anemia, thrombocytopenia


RESP: Chest tightness, increased thick secretions, wheezing


SKIN: Photosensitivity, rash, urticaria


 

Patient And Carer Advice: