Clinical Pharmacology Details


CYPROHEPTADINE HCL


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Indications & Dose:

Symptomatic relief of allergy such as hay fever, urticaria | Pruritus



Adult: 4 mg 3 times a day, OR


Syp. Under 2 years not recommended, 2-6 year


2mg 2-3 times daily, max:12mg daily, 7-14 years


4mg 23 times daily, max:16mg daily.


Migraine : 4mg with a further 4mg after 30 minutes if necessary, maintainance: 4mg ever 4-6 hours.


Syp: two Tsp thrice daily

Contraindications:

Acute asthma attack, lower respiratory tract disease lactation and neonates.

Side Effects:

Cautions:

Precautions:

neonates.Increased intraocular pressure due to closed-angle glaucoma, renal disease, cardiac disease, bronchial asthma, seizure disorder, stenosed peptic ulcers, prostatic hypertrophy, bladder neck obstruction, elderly 

Interaction:

Drugs


Fluoxetine: Potential for worsening of depression when cyproheptodine added to fluoxetine therapy


 

Warnings:

Adverse Effects:

Lactations:

Pregnancy; excreted in breast milk

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Anxiety, confusion, dizziness, drowsiness, euphoria, fatigue, neuritis, paresthesia, poor coordination


CV: Hypotension, palpitations, tachycardia


EENT: Blurred vision, dilated pupils; dry nose, throat, mouth; nasal stuffiness; tinnitus


GI: Anorexia, constipation, diarrhea, dry mouth, nausea, vomiting, weight gain


GU: Dysuria, frequency, retention


RESP: Chest tightness, increased thick secretions, wheezing


SKIN: Photosensitivity, rash, urticaria


MISC: Increased appetite 

Patient And Carer Advice: