Clinical Pharmacology Details


HYDROXYZINE HCL


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Indications & Dose:

Adults, Elderly & Children over 10 years


Antihistamine: 25mg 3-4 times daily


Anxiety: 50-100mg in equally divided doses.


Children:


Antihistamine: 6 years; 50-100mg daily in divided doses , less than 6 year 50mg daily in divided doses


Pruritus : 6month - 6 years; initially 15mg at night , increased if necessay up to 50mg daily in 3-4 divided doses . , 6-12 years initially 15-25mg at night , increased if necessary to 50-100mg aily in 3-4 divided doses , 12-18 years: initially 25mg at night, increased if necessary 50-100mg daily in divided doses.


Anxiety : below 6 years; 50 daily in divided doses , above 6 year 50-100mg daily in divided doses 6-10 years, 30-60mg in equally divided doses.


Childreb below 6 years:


2mg/kg/day divided 6-8 hours

Contraindications:

 Acute porphyria.


Pregnancy & breast-feeding: Contraindicated.

Side Effects:

ECG abnormalities. Intramuscular injection have been reported to cause marked local discomfort.

Cautions:

Precautions:

 : Liver disorders.


Old age: May be given.

Interaction:

Incompatibility reported with aminophylline, benzyl penicillin salts, chloramphenicol, sodium succinate, thioridazine and some soluble barbiturates

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: