DEXTROMETHORPHAN

Indications & Dose:

 Nonproductive cough

DOSE

Adult

• PO 10-20 mg q4h or 30 mg q6-8h, not to exceed 120 mg/day • PO EXT REL liq 60 mg bid, not to exceed 120 mg/ day

Child

• PO: Age b-12 yr 5-10 mg q4h, not to exceed 60 mg/day; age 2-b yr 2.55 mg q4h, not to exceed 30 mg/ day; EXT REL liq: Age 6-12 yr 30 mg bid, not to exceed 60 mg/day; age 2-5 yr 15 mg bid, not to exceed 30 mg/day 

Contraindications:

Side Effects:

Cautions:

Precautions:

Chronic, persistent, or productive cough; nausea, vomiting; fever; persistent headache 

Interaction:

Drugs Isocarboxazid, MAOIs, Phenelzine: Increased risk of toxicity due to dextromethorphan

Quinidine, terbinafine: Reduced hepatic metabolism of dextromethorphan

Fluoxetine: Case report of a patient on fluoxetine developing visual hallucinations when she began to take dextromethorphan; causality not established Sibutramine: Increased risk of serotonin syndrome 

Warnings:

Adverse Effects:

Lactations:

Pregnancy category C 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Dizziness

GI: Nausea 

Patient And Carer Advice: