Clinical Pharmacology Details


VALSARTAN+ HYDROCHLOROTHIAZIDE


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Indications & Dose:

Hypertension in patients whose BP is not controlled by Valsartan monotherapy.



Adults: 1 tab 80/12.5mg one daily. Increased up to 160/12.5mg as per patient response.


Children: Not recommended.


 

Contraindications:

Valsartan: Severe hepatic impairment, cirrhosis, biliary obstruciton. Pregnancy, lactation.

Side Effects:

Cautions:

Precautions:

Valsartan: Mild to moderate hepatic impairment, renal impairment, salt or volume depletion, renal artery stenosis, severe cardiac insufficiency. Monitor serum K+ in elderly and renally impaired if taking K+ suppl.

Interaction:

Valsartan: K+sparing diuretics, K+supplements, salt substitutes.

Warnings:

Adverse Effects:

Valsartan: Very rarely syncope, thrombocytopenia, renal dysfunction, angioedema.

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: