OLMESARTAN MEDOXOMIL+ HYDROCHLORTHIAZIDE

Indications & Dose:

Treatment of hypertension (not recommended for initial treatment)

• BY MOUTH

Adults: One tablet daily; dosage must be individualized . May be titrated at 2- to 4-week intervals.

Replacement therapy: May be substituted for previously titrated dosages of the individual Components.

Patients not controlled with single-agent therapy: Initiate by adding the lowest available dose of the alternative component (hydrochlorothiazide 12.5mg or olmesartsn 20 mg) Titrate to effect (maximum daily hydrochlorothiazide dose: 25 tog; maximum daily olmesartan dose:

40 mg).

Dosage adjustment in renal impairment: Not recommended in patients with Cl, <30 mL/minute Pregnancy Risk Factor C/D (2nd and 3rd tritoesters)

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