DIPYRIDAMOLE

Indications & Dose:

Secondary prevention of ischaemic stroke (not associated with atrial fibrillation) and transient ischaemic attacks (used alone or with aspirin) Adjunct to oral anticoagulation for prophylaxis of thromboembolism associated with prosthetic heart valves

• BY MOUTH USING MODIFIED-RELEASE MEDICINES

Adult: 200 mg twice daily, to be taken preferably with food

Adjunct to oral anticoagulation for prophylaxis of thromboembolism associated with prosthetic heart valves

• BY MOUTH USING IMMEDIATE-RELEASE MEDICINES

Adult: 300–600 mg daily in 3–4 divided doses

Myocardial imaging—diagnostic use only l

• BY INTRAVENOUS INJECTION

Adult: (consult product literature) 

Contraindications:

Side Effects:

CNS: Dizziness, headache

GI: Abdominal distress, anorexia, diarrhea, nausea, vomiting

SKIN: Flushing, rash

Cautions:

Precautions:

Ischemic heart disease, bleeding disorders, hypotension

Pregnancy; excreted in breast milk

Interaction:

Drugs 

Adenosine: Increased concentrations of adenosine, potentiates adenosine’s pharmacologic effects

Beta blockers: Additive bradycardia

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: