LOPERAMIDE

Indications & Dose:

Symptomatic treatment of acute diarrhoea 

• BY MOUTH

Child 4–7 years: 1 mg 3–4 times a day for up to 3 days only

Child 8–11 years: 2 mg 4 times a day for up to 5 days

Child 12–17 years: Initially 4 mg, followed by 2 mg for up to 5 days, dose to be taken after each loose stool; usual

dose 6–8 mg daily; maximum 16 mg per day

Adult: Initially 4 mg, followed by 2 mg for up to 5 days, dose to be taken after each loose stool; usual dose 6–8 mg daily; maximum 16 mg per day

Chronic diarrhoea

• BY MOUTH

¶% Adult: Initially 4–8 mg daily in divided doses, adjusted

according to response; maintenance up to 16 mg daily in 2 divided doses

Faecal incontinence

• BY MOUTH

Adult: Initially 500 micrograms daily, adjusted according to response, maximum daily dose to be given in divided doses; maximum 16 mg per day

Pain of bowel colic in palliative care

• BY MOUTH

Adult: 2–4 mg 4 times a day

PREGNANCY & BREAST-FEEDING: Safety not established. ; unknown ¬if excreted in breast milk; compatible with breast feeding

Old age: May be given in reduced dose 

Contraindications:

Acute diarrhea due to invasive organisms (enteroinvasive E. call, Salmonella, Shigella) or pseudomembranous colitis

Side Effects:

Cautions:

Precautions:

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Fatigue, fever, dizziness, drowsiness

GI: Abdominal pain, anorexia, constipation, dry mouth, nausea, toxic megacolon,vomiting

RESP: Respiratory depression 

SKIN: Rash

Patient And Carer Advice: