Clinical Pharmacology Details


BISACODYLE


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Indications & Dose:

Constipation


BY MOUTH


Child 4–17 years: 5–20 mg once daily, adjusted according to response, dose to be taken at night


Adult: 5–10 mg once dailyIncreased if necessary up to 20 mg once daily, dose to be taken at night


BY RECTUM


Child 2–17 years: 5–10 mg once daily, adjusted according to response


Adult: 10 mg once daily, dose to be taken in the morning


Bowel clearance before radiological procedures and surgery


INITIALLY BY MOUTH


Adult: 10 mg twice daily, does to be taken in the morning and evening on the day before procedure and (by rectum) 10 mg, to be administered.

Contraindications:

Rectal fissures, abdominal pain, nausea, vomiting, appendicitis, acute surgical abdomen, ulcerated hemorrhoids, acute hepatitis, fecal impaction, intestinal/biliary tract obstruction 

Side Effects:

Cautions:

Precautions:

Interaction:

Warnings:

Adverse Effects:

Lactations:

PREGNANCY AND LACTATION: Excreted in breast milk

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

GI: Anorexia, cramps, diarrhea, nausea, rectal burning (suppositories), vomiting


METAB: Alkalosis, hypokalemia, protein losing enteropathy, tetany


MS: Muscle weakness

Patient And Carer Advice: