PANTOPRAZOLE SODIUM

Indications & Dose:

Helicobacter pylori eradication in combination with amoxicillin and clarithromycin; or in combination with clarithromycin and metronidazole

BY MOUTH

Adult: 40 mg twice daily

Benign gastric ulcer

BY MOUTH

Adult: 40 mg daily for 8 weeks; increased if necessary up to 80 mg daily, dose increased in severe cases continued

Gastric ulcer

BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION

Adult: 40 mg daily until oral administration can be resumed, injection to be given over at least 2 minutes

Duodenal ulcer

BY MOUTH

Adult: 40 mg daily for 4 weeks; increased if necessary up to 80 mg daily, dose increased in severe cases

BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION

Adult: 40 mg daily until oral administration can be resumed, injection to be given over at least 2 minutes

Prophylaxis of NSAID-associated gastric ulcer in patients with an increased risk of gastroduodenal complications who require continued NSAID treatment | Prophylaxis of NSAID-associated duodenal ulcer in patients with an increased risk of gastroduodenal complications who require continued NSAID treatment

BY MOUTH

Adult: 20 mg daily

Gastro-oesophageal reflux disease

BY MOUTH

Adult: 20–80 mg daily for 4 weeks, continued for further 4 weeks if not fully healed, dose to be taken in the morning; maintenance 20 mg daily and increased to 40 mg daily, increased only if symptoms return

BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION

Adult: 40 mg daily until oral administration can be resumed, injection to be given over at least 2 minutes

Zollinger–Ellison syndrome (and other hypersecretory conditions)

BY MOUTH

Adult: Initially 80 mg daily (max. per dose 80 mg), adjusted according to response

Elderly: 40 mg daily

BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION

Adult: Initially 80 mg, alternatively 160 mg in 2 divided doses, if rapid acid control required, then 80 mg once daily (max. per dose 80 mg), adjusted according to response

Contraindications:

Pregnancy, lactation, impaired liver function. Hypersensitivity to the salt.

Side Effects:

CNS: Headache, dizziness, depression

CV: Edema

EENT: Visual disturbances

GI: Diarrhea, nausea, abdominal pain, flatulence

SKIN: Rash, pruritis

MISC: Fever

Cautions:

Precautions:

Symptomatic response does not rule out gastric malignancy; hepatic insufficiency.

Old age: Use with caution.

Interaction:

Drugs

3) Ketoconazole: Decreased bioBrands Available with Cost of ketoconazole

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: