OMEPRAZOLE/ SODIUM BICARBONATE/MAGNESIUM HYDROXIDE

Indications & Dose:

The dosage mentioned are calculated on the basis of Omeprazole In the product contents. 

Adults: 

Reflux esophagitis: 

20 mg once daily for 4 weeks, extend for a further 4-8 weeks if not fully healed. Refractory cases, 40mg once daily. 

Ado-reflux disease:

Long-term management, 10 mg once daily, increasing to 20 mg once daily if symptoms return.

Duodenal ulcer: 

20 mg once dally for 4 weeks. Se¬vere cases, increasing to 40 mg once daily. Preven¬tion of relapse, 10 mg once daily, increasing to 20 mg once daily if symptoms return. 

DU with H. Pylori: 40 mg daily with amoxycillin 1.5-2 gm daily for 2 weeks.

Gastric ulcer:

20 mg once daily for 6 weeks. Se¬vere cases, Increase to 40 mg once daily. 

Z-E syndrome:

60 mg once daily adjusted to re¬sponse. Usual maintenance. 20-120 mg daily. Dos¬es over 80 mg daily, give in two divided doses. Add aspiration: 40 mg in the evening of day before surgery, then 40 mg 1-4 hours prior to surgery. Children: Not recommended.

PREGNANCY: C (Risk cannot be ruled out).

Contraindications:

Side Effects:

Cautions:

Precautions:

Exclude malignancy before treatment. Hepatic impairment. Monitor serum B12 in severely ill children on tong term treatment,

Interactions: Diazepam, phenytoin, warfarin, digoxin, ketoconazole, itraconazole.

Interaction:

Warnings:

Adverse Effects:

Headache, GI Upset, skin rashes, paraesthesia, dizziness, somnolence, insomnia, arthralgia, myalgia. Increased risk of Gl infections. Increase in liver enzymes.

Lactations:

v (Contraindicated or not recommended)

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: